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Interpreting Genomes & Genome Functions

Science Meeting | UCD Conway Institute | 11-12 September 2017

Following the success of a 2014 event exploring opportunities for future collaborations, SBI and EMBL are teaming up to host a scientific meeting on ‘Interpreting Genomes and Genome Functions’ in the Lecture Theatre of the UCD Conway Institute on the 11th and 12th September 2017

The event will comprise of a series of talks from SBI researchers, EMBL researchers and EMBL alumni and will include an event hosted by the EMBL Alumni Association on the evening of the 11th September. A light lunch and refreshments will also be provided.

This is a free, open invitation event; however those planning to attend need to register before Friday August 25th.

For further information regarding the event please contact Ronan Gough by email on sbiadmin@ucd.ie or by telephone on +353 1 716 6331


Monday, 11 September

12:00-13:00 Registration and Lunch

13:00-13:05 Welcome Address:

Prof Des Higgins, EMBL Alumnus, SBI, UCD

13:05-13:30 SBI and EMBL overview:

Prof Walter Kolch, SBI, UCD

Prof Iain Mattaj, EMBL Heidelberg

13:30-15:00 Science Session 1

Chair: Prof Des Higgins, EMBL Alumnus, SBI, UCD

13:30-14:00 Dr. Anne-Claude Gavin, EMBL Heidelberg:

Lipid metabolism in time and space.

14:00-14:30 Dr. Tapesh Santra, SBI, UCD:

Data analysis and mathematical modelling predicts combination therapy for treating drug resistant cancer cells.

14:30-15:00 Dr. Pedro Beltrao, EMBL-EBI :

Autosomal gene dosage compensation in cancer.

15:00-15:30 Coffee break

15:30-17:00 Science Session 2

Chair: Dr Anne-Claude Gavin, EMBL Heidelberg

15:30-16:00 Prof Owen Smith, Our Lady's Children's Hospital Crumlin & SBI, UCD:

Unravelling the biological heterogeneity of the commonest cancer in children by genotype and treatment molecular response: towards personalised cancer care.

16:00-16:30 Dr Dirk Fey, SBI, UCD:

Insights into drug-resistance mechanisms from patient-specific modelling of JNK and p53 dynamics in Neuroblastoma.

16:30-17:00 Dr Melinda Halasz, SBI, UCD:

Unravelling the role of MYCN in the pathogenesis of neuroblastoma.

17:10-19:00 Reception hosted by the EMBL Alumni Association

Tuesday, 12 September

08:30-09:00 Registration

09:00-10:30 Science Session 3:

Chair: Dr Melinda Halasz, SBI & School of Medicine, UCD

09:00-09:30 Dr. John Marioni, EMBL-EBI:

Using single cell transcriptomics to understand cell fate decisions.

09:30-10:00 Prof Jeremy Simpson, EMBL Alumnus, UCD:

Multi-dimensional genome-wide RNAi screening of mammalian intracellular pathways.

10:00-10:30 Dr Anton Enright, EMBL-EBI:

Machine learning approaches for the discovery of novel microRNAs.

10:30-11:00 Coffee break

11:00-12:30 Science Session 4

Chair: Prof Walter Kolch, SBI, UCD

11:00-11:30 Dr Paul Young, EMBL Alumnus, UCC:

Proteomic and Molecular Genetic Analysis of the LNX family of E3 Ubiquitin Ligase.

11:30-12:00 Dr Colm Ryan, SBI, UCD :

Targeting Gene Loss in Cancer.

12:00-12:30 Dr Stephen Rea, EMBL Alumnus:

Accessing the genome through histone acetylation.

12:30-13:30 Lunch and Close of Meeting

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